Do the simple things right.
EA had seriously problems with each CNC game since Generals. Gen 2 is a great chance to bring the franchise back and grow it larger.
#1 - No deadline date - this is imperative - the devs need the time to polish this game. Previous iterations of the genre from the owners of the CNC franchise were far to aggressive and the quality suffered. You take a game like RA3 and compare it to Gens 1. Gens had 4v4, RA3 had only 3v3. That can not happen again. Take Generals and improve, do not take a step back.
#2 - Do the things you do well and stick with them. Generals was a solid, simple RTS game with great pace. In comparing it to RA3 - I think it's clear that Generals was a better play in terms of execution and strategy.
#3 - Patches, Support... it's got to be there. You must remove disconnects. In following point #2, this aspect must be polished on day 1. That may mean dropping gamespy - I don't know. Cheating has to be mitigated as well. Can't have another RA3 like issue with that Tijuana Core problem.
I think the modern warfare angle in Generals really plays well, but the gameplay and multiplayer need to stay crisp. The above list is the basic stuff. Hopefully this thread can expand into some of the underlying needs of the game. Super excited for the frostbite engine - it runs silky smooth online in bf3, hopefully they can do the same in Gens2.